Once-a-Day Concerta Methylphenidate Versus Three-Times-Daily Methylphenidate in Laboratory and Natural Settings
نویسندگان
چکیده
منابع مشابه
Once-a-day Concerta methylphenidate versus three-times-daily methylphenidate in laboratory and natural settings.
OBJECTIVE Methylphenidate (MPH), the most commonly prescribed drug for attention-deficit/hyperactivity disorder (ADHD), has a short half-life, which necessitates multiple daily doses. The need for multiple doses produces problems with medication administration during school and after-school hours, and therefore with compliance. Previous long-acting stimulants and preparations have shown effects...
متن کاملOnce a day Concerta methylphenidate was equivalent to 3 times daily methylphenidate in children with ADHD.
Once a day Concerta methylphenidate was equivalent to 3 times daily methylphenidate in children with ADHD"
متن کاملEfficacy of a methylphenidate transdermal system versus t.i.d. methylphenidate in a laboratory setting.
OBJECTIVE To test the efficacy and tolerability of the methylphenidate transdermal formulation (MTS) against immediate-release methylphenidate (IR MPH) and placebo in a 12-hr analog classroom setting. METHOD A total of nine boys ages 6 to 9 years, medicated with MPH for ADHD, complete a within-subject, double-blind study. For the purpose of the study, the boys are administered a dose of 20 cm...
متن کاملA case of suicide attempt with long-acting methylphenidate (Concerta).
The prescribed use of methylphenidate in the treatment of attention deficit hyperactivity disorder (ADHD) is widespread. The intranasal and parenteral abuse of methylphenidate (Ritalin) among teenagers is becoming increasingly more common, and deaths have been reported. Newer medical treatment options of long-acting stimulants offer effective treatment with a lower risk of abuse potential. We d...
متن کاملEfficacy of two once-daily methylphenidate formulations compared across dose levels at different times of the day: Preliminary indications from a secondary analysis of the COMACS study data
BACKGROUND Methylphenidate (MPH) is commonly prescribed in the treatment of Attention-Deficit/Hyperactivity Disorder or ADHD. Concerta and Metadate CD are once-daily formulations of MPH using different delivery mechanisms resulting in different pharmacokinetic profiles. A recent study (COMACS) showed that for near-milligram (mg) equivalent daily doses, Metadate CD provides greater symptom contr...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2001
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.107.6.e105